Tehran University of Medical Sciences International Journal of Occupational Hygiene 2008-5109 12 2 2020 07 30 122 131 Hamidreza Pouragha Tehran University of Medical Sciences Hassan Ashayeri Professor of Neurology and neuropsychology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Abbas Rahimi Foroushani Professor of Biostatistics, Department of Epidemiology and Biostatistics, School of Public Health, Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran. Mahsa Naserpour M.Sc. of Occupational Health, Shahid Beheshti University of medical sciences, Tehran, Iran Seyyed Jamalledin Shahtaheri Professor of Occupational Health, Department of Occupational Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2020 08 10 2020 10 22 The purpose of this study was to investigate the association between five personality traits of Zuckerman theory and the General Mental Health Index between two groups of individuals in terms of accident proneness score and to present a predictive model of accident proneness trait in the studied population. This cross-sectional study was conducted on 270 Iranian male workers of chemical industries having work experience of at least one year and a maximum age of 45 years voluntarily participated in the research. The baseline data and background information of all participants were collected and they were asked to fill out the GHQ-28 questionnaire, Zuckerman-Kuhlman personality questionnaire, and TAS subscale of the Zuckerman Sensation-Seeking Scale-V (SSS-V). The results showed that work experience (p=0.002), marital status (p=0.041), social dysfunction (p=0.037), severe depression (p=0.023), and aggression hostility (p=0.020) were significantly varied between the two groups of accident-prone and non-accident-prone. Also, using the variables investigated by the binary logistic regression model, the attribute of having or not having accident proneness was predicted at R Square of 0.416. It was found that personality traits of Aggression Hostility and Psychological Symptom of Social Dysfunction and Severe Depression have associated with accident proneness in the population under study. https://ijoh.tums.ac.ir/index.php/ijoh/article/view/448 https://ijoh.tums.ac.ir/index.php/ijoh/article/download/448/614