Tehran University of Medical Sciences International Journal of Occupational Hygiene 2008-5109 17 1 2025 03 03 1 7 Abolfazl Ghahremani Elyas Taghizadeh School of Public Health, Urmia University of Medical Sciences, Urmia, Iran Iraj Mohebbi Social Determinants of Health Research Center, Occupational Medicine Center, Urmia University of Medical Sciences, Urmia, Iran 2024 05 27 2024 11 03 Over the last few decades, organizations' productivity and occupational health and safety (OHS) performance have improved as a result of the adoption of innovative manufacturing technologies and new management approaches. Despite these improvements, OHS performance in developing nations remains unsatisfactory, and further research is needed to ascertain the factors that influence OHS performance. The purpose of this study was to determine the factors influencing OHS performance in Iranian manufacturing companies.  Twelve informants, including OHS inspectors and managers, were interviewed individually for this qualitative study. The interviews were semi-structured, and the data were analyzed using the grounded theory method. Management commitment, safety culture, OHS training, OHS regulations, economic and political issues, social factors, as well as personal and occupational factors have all been identified. The findings emphasize the importance of identifying influencing factors in order to improve manufacturing companies' OHS performance. Given the limited financial resources available to the companies, government assistance and effective OHS training may help in promoting OHS performance. Efforts to improve safety culture and to enforce OHS regulations may impact OHS performance. https://ijoh.tums.ac.ir/index.php/ijoh/article/view/635 https://ijoh.tums.ac.ir/index.php/ijoh/article/download/635/814