Tehran University of Medical Sciences International Journal of Occupational Hygiene 2008-5109 15 2 2025 12 08 26 28 Payam Khanlari Tehran university of medical sciences Hanieh Abdi Department of Occupational Health Engineering, School of public health, Tehran University of Medical Sciences 2025 05 12 2025 08 11 Metaverse is not a product of today's age but has gone through several phases and stages over a long period of history, where efforts to improve the service and accompanying developments continue daily. Considerable efforts are currently being made by researchers, designers, developers, decision-makers, and others to enhance the metaverse, and many metaverse platforms are now available. Metaverse is used in various fields and on the other hand, it will bring challenges. In order to achieve better performance and maintain human well-being when using Metaverse, interactions should be considered from different aspects. Therefore, future research is needed to examine people's interactions with metaverse environments and platforms with a comprehensive approach. In the end, research agents of human factors and ergonomics were presented to investigate user interactions with Metaverse. https://ijoh.tums.ac.ir/index.php/ijoh/article/view/694 https://ijoh.tums.ac.ir/index.php/ijoh/article/download/694/855